Progressive Ellipsoid zone loss. (a) SD-OCT imaging in patients A-II:2, B-II:1 and D-II:5 of the first visit and last visit (right eye) what was interval between visits. Red arrows show the boundaries of intact EZ lines. (b) SW-AF imaging in patients A-II:2, B-II:1 and D-II:5 of the first visit and last visits (left eye), accompanied by significant fusion and punctate enlargement of the hypoautofluorescence area in the parafoveal, mid-peripheral, and widespread retina within the disease course.