Summary of biological information of lactams classified according to their chemical class.

	β-Fused	β-Isolated	β-Spiro	γ-Fused	γ-Isolated	γ-Spiro	δ-Fused	δ-Isolated	δ-Spiro	ε-Fused	ε-Spiro	ε-Bridged
No. human targets	52	88	4	501	352	15	351	179	9	190	5	5
No. non-human targets	94	52	2	172	184	11	153	71	8	76	2	6
% active compounds	37.18	43.58	62.74	46.76	43.39	7.87	39.93	48.76	6.32	50.69	62.16	17.20
No. unique compounds	627	892	41	4062	3297	198	2406	2042	255	1861	25	78
No. unique scaffolds	280	376	19	1638	1658	138	1259	1031	206	926	12	58