Fig. 7. Synergetic therapy of HeLa tumor-bearing mice with SCPB@DOX@EM@FA NPs. (A) Time schedule of treatments and experiments. (B) Infrared thermography of HeLa-bearing mice that were tail vein injected with PBS, SCPB@DOX NPs, SCPB@DOX@EM NPs, and SCPB@DOX@EM@FA NPs. (C) Relative body weight and (D) relative tumor volume of cervical tumor-bearing mice with different treatment. (E) Representative photographs of cervical tumor-bearing mice and tumors for each tested group (with NIR laser: 808 nm, 0.8 W cm⁻²). H&E staining and TUNEL assay of the tumor tissues after different treatment (scale bar = 100 μm). *P < 0.1, **P < 0.01, ***P < 0.001. All data represent means ± SD (n = 3).