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Effect of pregnancy and HIV on INH PK: The clearance of isoniazid was comparable between pregnant and postpartum women with HIV (orange) and without HIV (blue). The AUCSS for the entire population was 78.2 mg × hour/L (IQR, 21.9–78.2) and maximum isoniazid concentration was 7.74 mg/L (IQR, 5.68–10.6). Abbreviations: AUCSS, steady-state area under the concentration-time curve; HIV, human immunodeficiency virus; IQR, interquartile range.
