Figure 1.

SARS-CoV-2 RNA levels in plasma are associated with disease severity and outcome. Plasma SARS-CoV-2 RNA levels (copies per milliliter) by location of clinical care at baseline (A), severity of illness by WHO ordinal scale at baseline (B), and worst WHO scale during hospitalization (C) for outpatient (n = 9), inpatient non-ICU (n = 19), and inpatient ICU (n = 24). Kaplan-Meier curves for time to discharge from hospital admission (D) and 60-day survival (E) for inpatients (both ICU and non-ICU) stratified by high (>6000 copies/mL) vs low (≤6000 copies/mL) initial viral RNA level. Plasma SARS-CoV-2 RNA levels (copies per milliliter) by outcome of hospitalization among inpatients (F). Patients with undetected SARS-CoV-2 RNA in plasma are represented by open circles and graphed as one-half the Lower limit of detection (LLOD). Abbreviations: cps, copies; ICU, intensive care unit; LTAC, long-term acute care; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; SNF, skilled nursing facility; WHO, World Health Organization.