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. 2022 May 5;17(5):e0267837. doi: 10.1371/journal.pone.0267837

Fig 1. Calculation of retinal vessel metrics with MONA REVA software and FracLac plugin in FIJI software.

Fig 1

The concentric circles on the segmented images indicate the regions of interest (ROIs) in which the metrics were calculated. R is defined as the radius of the optic disc (inner red circle). For ROI 1 and ROI 2, radii of the larger circles are a multiple of R. The entire segmented without the optic disc is ROI 3. Note: the segmented image is a representative example and not the segmented image of the shown greyscale image.