Table 3.

Proteins co-immunoprecipitated, pulled-down, or co-purified with WHIRLIES in protein complexes of plastids or mitochondria.

	Full name and synonymous names	WHIRLIES	Organelle protein complex	Function	References
BCCP1	Biotin carboxyl carrier protein 1 of acetyl-CoA carboxylase	WHIRLY3	Nucleoid	Fatty acid biosynthesis	Phinney and Thelen, 2005
CLPC1	CLP protease chaperon 1	WHIRLY3	Nucleoid	Proteolysis stress	Zheng et al., 2002; Olinares et al., 2011
CRS1	Chloroplast RNA Splicing 1	WHIRLY1	Ribonucleoprotein complex	Group IIA intron splicing factor	Till et al., 2001; Prikryl et al., 2008
2CPA	2-Cys-Peroxiredoxin A	WHIRLY1 WHIRLY3		Redox sensing and redox regulation	Liebthal et al., 2020; Telman et al., 2020
FIB1a	Fibrillin 1a	WHIRLY3	Network around plastoglobuli, interaction with fibrillin 1b indicative of oligomerization	Involved in partitioning of proteins in plastids protection against photodamage, stress resistance	Singh and McNellis, 2011; Gamez-Arjona et al., 2014
FIB4	Fibrillin 4	WHIRLY3	Interaction with plastoglobules, LHC, photosystem II, thylakoids	Development of plastoglobules, resistance to multiple stresses	Singh et al., 2010
pTAC4	Plastid transcriptionally active chromosome 4 VIPP, vesicle inducing plastid protein	WHIRLY3	Nucleoid/TAC	Chloroplast development	Kroll et al., 2001
PPR4	Plastid pentatricopeptide repeat 4	WHIRLY3	Ribonucleoprotein complex	rps12 trans-splicing	Xu et al., 2019
LHCA1	Light-Harvesting complex of photosystem I, subunit 1	WHIRLY1	Photosystem I	Photosynthesis, light adaptation	Huang et al., 2017
LHCB5	Light-Harvesting complex of photosystem II, subunit 5 CP26	WHIRLY3	Photosystem II	Photosynthesis, tolerance to drought, oxidative stress protection	Xu et al., 2012; Chen et al., 2018
ODB1	Organelle DNA-binding protein 1, RAD52-1	WHIRLY2	Large nucleoprotein complexes, likely nucleoids	Recombination and repair of mitochondrial DNA	Janicka et al., 2012
PetA	Cytochrome f	WHIRLY3	Cytochrome b6f complex	Photosynthesis, electron transport
PRPS5	Plastid ribosomal protein S5, EMB3113	WHIRLY3	Essential component of plastid ribosome	16S rRNA processing, translation cold stress tolerance embryo development	Bryant et al., 2011; Zhang et al., 2016
PRPS3	Plastid ribosomal protein S3	WHIRLY3	Essential component of plastid ribosome	Translation affects leaf shape	Fleischmann et al., 2011
RECA	Recombinase A	WHIRLY2		Mitochondrial DNA recombination	Meng et al., 2020
RNaseH	Ribonuclease H	WHIRLY1 WHIRLY3	DNA gyrase complex	Maintenance of ptDNA, removal of R-loops	Yang et al., 2017