Table 1.
Comparison of demographics and clinical characteristics between groups.
| Characteristics | All patients (n = 205) | Group 1 (n = 88) | Group 2 (n = 117) | p value |
|---|---|---|---|---|
| Age, years | 56 ± 12 | 56 ± 12 | 56 ± 12 | 0.981 |
| Sex | ||||
| Female | 117/205 (57.1%) | 46/88 (52.3%) | 71/117(60.7%) | 0.256 |
| Male | 88/205 (42.9%) | 42/88 (47.7%) | 46/117 (39.3%) | |
| Smoking history | 36 /195 (18.5%) | 15/81 (18.5%) | 21/114 (21%) | 0.986 |
| History of alcohol consumption | 51/195 (26.2%) | 18/81 (22.2%) | 33/114 (28.9%) | 0.292 |
| Fever | 169/203 (83.3%) | 72/86 (83.7%) | 97/117 (82.9) | 1.000 |
| Maximum temperature (°C) | 38.1 ± 3 | 38.3 ± 1.0 | 37.9 ± 3.9 | 0.462 |
| Cough | 153/203 (75.4%) | 68/86 (79.2%) | 85/117 (72.6%) | 0.294 |
| Dyspnea | 112/203 (55.2) | 55/86 (64%) | 57/117 (48.7%) | 0.031 |
| HR (bpm) | 94 ± 15 | 98 ± 14 | 92 ± 16 | 0.003 |
| Respiratory rate | 24 ± 6 | 25 ± 7 | 23 ± 4 | 0.002 |
| SBP (mmHg) | 135 ± 19 | 138 ± 17 | 132 ± 19 | 0.045 |
| DBP (mmHg) | 84 ± 12 | 84 ± 10 | 84 ± 13 | 0.776 |
| Oxygen saturation on room air (%) | 90 ± 11 | 87 ± 13 | 92 ± 9 | 0.001 |
| Any comorbidities | 114/195 (58.5%) | 47/81 (58%) | 67/114 (67%) | 0.917 |
| Diabetes | 32/195 (16.0%) | 13/81 (16%) | 19/114 (16.7%) | 0.909 |
| Hypertension | 72 /195 (36.9%) | 31/81 (38.3%) | 41/114 (36%) | 0.742 |
| Bacterial infection | 11/201 (5.5%) | 6/86 (7%) | 5/115 (4.3%) | 0.417 |
| Hospital stay duration (days) | 25 ± 18 | 31 ± 21 | 20 ± 14 | < 0.001 |
| ARDS | 38/201 (18.9%) | 23/86 (26.7%) | 15/115 (13%) | 0.014 |
| Treatment | ||||
| Antiviral agents | 163/201 (81.1%) | 71/86 (82.6%) | 92/115 (80%) | 0.647 |
| Antibacterial agents | 149/201 (74.1%) | 66/86 (76.7%) | 83/115 (72.2%) | 0.464 |
| Glucocorticoids | 71/201 (35.3%) | 42/86 (48.8%) | 29/115 (25.2%) | 0.001 |
| Oxygen therapy | 141/201 | 68/86 (79.1%) | 73/115 (63.5%) | 0.017 |
| Mechanical ventilation | ||||
| Noninvasive | 33/86 (16.4%) | 21/86 (24.4%) | 12/115 (10.4%) | 0.008 |
| Invasive | 6/201 (3%) | 5/86 (5.8%) | 1/115 (0.9%) | 0.042 |
The data are presented as the means ± SD, medians (interquartile ranges) or n/N (%). p values comparing patients with DLCO < 80%(group 1) and patients with DLCO ≥ 80% (group 2) are from χ2, Fisher’s exact test, independent-samples T test or Mann–Whitney U test.
HR heart rate, SBP systolic blood pressure, DBP diastolic blood pressure, ARDS acute respiratory distress syndrome.