Table 4.
Multiple Cox regression model stratified by region on death in control patients including single variables of interest
| HR | 95% CI | P-value | |
|---|---|---|---|
| Age (years) | 1.04 | 1.02–1.06 | <0.01 |
| BMI (kg/m2) | 0.93 | 0.89–0.98 | <0.01 |
| Creatinine (mg/dL) | 1.30 | 1.06–1.60 | 0.01 |
| Diastolic blood pressure (mmHg) | 0.98 | 0.96–1.00 | 0.02 |
| Haemoglobin (g/dL) | 0.90 | 0.79–1.02 | 0.09 |
| Heart rate (b.p.m.) | 1.01 | 1.00–1.03 | 0.06 |
| LVEF (%) | 0.92 | 0.89–0.95 | <0.01 |
| Sex (male vs. female) | 2.27 | 1.25–4.12 | <0.01 |
| Sodium (mmol/L) | 1.06 | 0.10–1.13 | 0.07 |
| Adjusting for the variables shown above and stratifying by region, we observe the following results for each parameter individually | |||
| QTc | 1.02 | 1.01–1.02 | <0.01 |
| QRSd (ms) | 1.01 | 1.00–1.02 | 0.03 |
| QTc 450/470 (yes vs. no) | 1.77 | 1.15–2.74 | 0.01 |
| QRS120 (yes vs. no) | 1.61 | 1.06–2.44 | 0.03 |
| IVCD (yes vs. no) | 1.47 | 0.94–2.30 | 0.09 |
n = 666, statistically significant results presented in bold.
95% CI, 95% confidence interval; BMI, body mass index; HR, hazard ratio; IVCD, non-specific intraventricular conduction delay; LVEF, left ventricular ejection fraction; QRS120, QRS duration ≥120 ms (1) or less 0; QRSd, QRS duration; QTc 450/470, QTc ≥450 ms in male and ≥470 ms in female (1) or less 0; QTc, QT-interval corrected by Framingham’s formula.