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. 2021 Nov 30;37(2):89–111. doi: 10.1093/mutage/geab040

Figure 4.

Figure 4

3Dskin RSMN results for 1,5-Dimethylbicyclo[3.2.1]octan-8-one-oxime (CAS# 75147-23-8): (A) 48-hour treatment and (B) 72-hour treatment condition. The long-dashed black line shows the lab-specific 95%-quantile of the mean of the historical control range for the MNBN data, and the thresholds for excessive cytotoxicity (40%) are shown by the black dotted line. A red asterisk indicates a statistically significant increase in % MNBN vs. the SC (Fisher’s exact test; P < .05). Error bars shown depict the standard error of the mean.