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. 2022 Apr 23;37(2):164–171. doi: 10.1093/mutage/geac007

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© The Author(s) 2022. Published by Oxford University Press on behalf of the UK Environmental Mutagen Society.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — miR-431-5p targets PRDX1. (A) Binding site between miR-431-5p and PRDX1 was predicted at Starbase; (B) binding relation between miR-431-5p and PRDX1 was confirmed by dual luciferase reporter gene assay; (C) PRDX1 expression in CRC cell lines and normal epithelial cells; (D) PRDX1 expression in CRC tissues and adjacent normal tissues; (E) correlation between expression of miR-431-5p and PRDX1 was analyzed by Pearson test; (F) expression of PRDX1 in LoVo cells; *P < 0.05 versus the NC-mimic group.