. 2001 Sep;45(9):2662–2665. doi: 10.1128/AAC.45.9.2662-2665.2001

TABLE 1.

Effects of eight antibiotics alone and with Q-D on bacterial counts after 24-h exposure

Strain	Inoculum (log₁₀ CFU/ml)	Treatment type	Bacterial counts (log₁₀ CFU/ml) after 24-h exposure to^a:
Strain	Inoculum (log₁₀ CFU/ml)	Treatment type	Q-D	Van	Cef	Ctz	Imp	P/T	Cip	Gen	Rif
SP1256 (MSSA)	6.38	Alone	4.70	3.40	2.18	5.00	1.00	2.69	9.18	1.00	8.60
		With Q-D		4.70	5.18	5.30	4.74	5.00	4.59	1.00	3.65
SP1549 (MSSA)	5.51	Alone	4.54	3.40	2.54	2.38	1.00	1.30	1.00	1.70	9.28
		With Q-D		4.32	5.32	5.54	4.93	5.08	4.79	1.00	5.40
SP1661 (MRSA)	6.18	Alone	3.48	1.30	7.73	9.00	8.98	9.04	9.11	9.23	9.00
		With Q-D		3.00	4.08	3.40	4.18	4.18	4.08	3.42	4.23
SP1662 (MRSA)	6.43	Alone	6.95	2.43	9.08	9.26	9.34	9.46	9.11	8.30	8.90
		With Q-D		6.04	5.70	5.78	6.23	6.00	6.11	5.56	4.94
SP1664 (MRSA)	6.15	Alone	6.45	3.18	8.59	8.95	9.15	9.18	2.28	1.00	4.60
		With Q-D		4.95	6.00	5.00	5.18	6.32	6.30	1.00	3.00
SP1938 (MRSA)	6.00	Alone	5.46	4.11	7.86	8.71	4.85	8.40	3.04	1.00	1.74
		With Q-D		4.04	5.00	5.26	5.18	4.90	3.20	1.00	1.00
SP1939 (MRSA)	5.87	Alone	4.82	1.70	8.70	8.94	8.00	8.88	9.15	8.00	5.30
		With Q-D		4.98	5.90	5.20	5.90	5.65	4.83	4.59	3.78
SP1942 (MRSA)	5.04	Alone	4.43	2.64	9.26	8.92	9.20	9.38	8.69	1.00	9.32
		With Q-D		5.75	5.91	3.74	6.20	5.81	3.18	1.00	4.11
SP2069 (MRSA)	6.32	Alone	4.48	1.78	3.00	9.26	1.00	9.18	9.43	1.00	9.08
		With Q-D		5.04	5.49	3.74	5.08	5.15	4.11	1.00	NT
SP2115 (MRSA)	6.20	Alone	6.23	1.65	9.04	8.74	9.11	9.08	9.04	1.74	5.89
		With Q-D		5.95	6.38	5.98	6.11	6.11	6.20	1.00	4.69

Van, vancomycin; Cef, cefepime; Ctz, ceftazidime; Imp, imipenem; P/T, piperacillin-tazobactam; Cip, ciprofloxacin; Gen, gentamicin; Rif, rifampin. Bold values indicate bactericidal activity, underlined values indicate antagonism, and italicized values indicate synergism (see text for definitions). NT, not tested.