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. 2022 Feb 27;37(5):954–968. doi: 10.1093/humrep/deac035

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© The Author(s) 2022. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 2. — Forest plots describing breast cancer recurrence, event-free survival and mortality in patients undergoing controlled ovarian stimulation before starting oncological treatments. Solid vertical line: Significance line (line of no effect). Gray squares: represents the weighted mean (point estimate) of each study. Horizontal bars: 95% CI line. Diamond: represents the mean of effect sizes obtained by the meta-analysis. Its width corresponds to its 95% CI. (A) Recurrence rate in patients undergoing COS. (B) Event-free survival in patients undergoing COS. (C) Mortality rate in patients undergoing COS. COS, controlled ovarian stimulation; HR, hazard ratio; RR, relative risk. I-squared is Higgins I² index (Higgins and Thompson, 2002).