Figure 2.

Mycobacterium tuberculosis-specific CD4+ T-cell responses are diminished during the third trimester of pregnancy. A-B, PFS (A) and FS (B) generated from COMPASS analysis of CD4+ T cell responses, stratified by pregnancy trimester. C-D, PFS (C) and FS (D) generated from COMPASS analysis of CD8+ T cell responses, stratified by pregnancy trimester. Circles indicate an HIV-negative study participant, while triangles indicate a WLWH. Bars indicate median values, Kruskal-Wallis test. Column-to-column comparisons are made with Dunn test. Abbreviations: FS, functional score; HIV, human immunodeficiency virus; PFS, polyfunctional score; WLWH, women living with HIV.