Table 3.
Sensitivity analyses (odds ratios and 95% CI) for association of 1 SD difference in visceral fat with metabolic syndrome and type 2 diabetes in participants without obesity in the Jackson Heart Study
| Model | Metabolic syndrome | Type 2 diabetes | ||
|---|---|---|---|---|
| OR | 95% CI | OR | 95% CI | |
| Primary analysis * | 2.07 | 1.66-2.58 | 1.51 | 1.21-1.88 |
| Incident cases only | 2.00 | 1.49-2.69 | 1.70 | 1.29-2.25 |
| Excluding waist circumference from MetS definition ** | 1.74 | 1.41-2.15 | 1.51 | 1.21-1.88 |
| No hormone replacement therapy usage in women | 1.88 | 1.47-2.40 | 1.57 | 1.23-2.01 |
| By sex | ||||
| Women | 2.60 | 1.83-3.70 | 1.80 | 1.28-2.54 |
| Men | 1.74 | 1.30-2.33 | 1.29 | 0.96-1.73 |
| P value for difference by sex | 0.06 | 0.13 |
BOLD indicates significant at the P < 0.05 level.
*Primary analysis includes adjustment for age, sex, education, income, smoking, visceral fat, subcutaneous fat, HOMA-IR, and physical activity.
**Sample size for incident analysis is 795 for MetS and 944 for T2D, and analysis excluding women with known hormone replacement therapy is 923.