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. 2022 Apr 21;12:841418. doi: 10.3389/fonc.2022.841418

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Copyright © 2022 Kram, Prokop, Haller, Gempt, Wu, Schmidt-Graf, Schlegel, Conrad and Liesche-Starnecker

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Co-expression of GFAP and Iba1 with ACSL4 and GPX4. Given are the numbers of GFAP⁺ or Iba1⁺ cells of ACSL4⁺ or GPX4⁺ cells. The dots indicate the amounts of each patient in the primary and relapse tumor. (A) The number of GFAP⁺/ACSL4⁺ cells decreases insignificantly in the relapse. (B) The amount of Iba1⁺/ACSL4⁺ cells significantly decreases in the relapse. (C) The number of GFAP⁺/GPX4⁺ cells decreases significantly in the relapse. (D) The amount of Iba1⁺/GPX4⁺cells increased significantly in the relapse.