TABLE 2.
Demographics of Chest Pain Study Populations in Phase 1 vs Phase 2
| Fourth Generation | hsTnT | P Value | |
|---|---|---|---|
| (n = 3,641) | (n = 4,203) | ||
| Age, mean (SD), y | 59 (16) | 59 (15) | .99 |
| BMI, mean (SD), kg/m2 | 28.3 (7.5) | 27.9 (7.3) | .04 |
| Male sex, No. (%) | 1,968 (54.1) | 2,294 (54.6) | .66 |
| Ethnicity, No. (%) | |||
| American Indian | 8 (0.2) | 22 (0.5) | .05 |
| Asian | 272 (7.5) | 299 (7.1) | .58 |
| Black | 521 (14.3) | 625 (14.9) | .50 |
| Pacific Islander | 21 (0.6) | 33 (0.8) | .33 |
| Other/mixed | 888 (24.4) | 991 (23.6) | .42 |
| Unknown | 9 (0.2) | 24 (0.6) | .42 |
| White | 1,922 (52.8) | 2,208 (52.5) | .85 |
| Medical history (ICD-10 code), No. (%) | |||
| Hypertension (I10) | 454 (35.4) | 546 (37.5) | .29 |
| Chronic ischemic heart disease (I25) | 292 (22.8) | 258 (17.7) | <.01 |
| AF (I48) | 277 (21.6) | 386 (26.5) | <.01 |
| DM (E11) | 264 (20.6) | 270 (18.5) | .19 |
| Hyperlipidemia (E78) | 139 (10.9) | 181 (12.4) | .22 |
| COPD (J44) | 166 (13.0) | 183 (12.6) | .80 |
| MI (I21) | 93 (7.3) | 91 (6.2) | .33 |
| CKD (N18) | 185 (14.4) | 213 (14.6) | .94 |
| TnT results in ED, No. (%) | <.001 | ||
| 1 | 2,749 (75.5) | 2,175 (51.7) | |
| ≥2 | 892 (24.5) | 2,028 (48.3) |
AF, atrial fibrillation; BMI, body mass index; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; ED, emergency department; hsTnT, high-sensitivity troponin T; ICD-10, International Classification of Diseases, Tenth Revision; MI, myocardial infarction; SD, standard deviation.