Table 2.

Univariate and Multivariable Analysis of Clinical Prognostic Factors in the Whole Cohort

	PFS						OS
	Univariate			Multivariable			Univariate			Multivariable
Factor	HR	CI 95%	p-value	HR	CI 95%	p-value	HR	CI 95%	p-value	HR	CI 95%	p-value
Age	2.368	1.420–3.949	0.001	1.855	1.064–3.234	0.029	3.215	1.795–5.759	< 0.001	2.170	1.124–4.191	0.021
Seizures at onset	0.842	0.539–1.316	0.451	0.604	0.552–1.413	0.883	0.972	0.620–1.525	0.903	0.903	0.560–1.457	0.676
Contrast enhancement	1.774	1.059–2.971	0.029	1.693	0.994–2.882	0.052	2.331	1.439–3.776	0.001	2.500	1.536–4.067	< 0.001
GTR	0.425	0.253–0.714	0.001	0.507	0.287–0.897	0.020	0.356	0.207–0.612	0.001	0.417	0.229–0.760	0.004

GTR: gross total resection.