TABLE 4.
Adjusted HRs and 95% CIs for associations of SFA intake with risk of colorectal cancer, Black Women's Health Study
| Cases, n | Person-y | HR (95% CI)1 | |
|---|---|---|---|
| Total saturated fat intake, g/d | |||
| 0.7–<10.0 | 115 | 211,840 | 1.00 |
| 10.0–<20.0 | 272 | 532,039 | 0.98 (0.75, 1.27) |
| ≥20.0 | 173 | 370,777 | 0.89 (0.58, 1.39) |
| Ptrend2 | 0.5 | ||
| Continuous, per 10 g/d | 0.66 (0.23, 1.91) | ||
| Individual SFA intake | |||
| Fatty acid 4:0 (butyric acid) | |||
| Tertile 1 | 186 | 317,912 | 1.00 |
| Tertile 2 | 209 | 455,927 | 0.89 (0.72, 1.10) |
| Tertile 3 | 161 | 332,950 | 0.94 (0.71, 1.24) |
| Ptrend2 | 0.9 | ||
| Continuous (per 1 g/d) | 0.78 (0.53, 1.17) | ||
| Fatty acid 6:0 (caproic acid) | |||
| Tertile 1 | 95 | 169,697 | 1.00 |
| Tertile 2 | 241 | 499,349 | 0.99 (0.77, 1.27) |
| Tertile 3 | 220 | 435,876 | 1.08 (0.81, 1.46) |
| Ptrend2 | 0.5 | ||
| Continuous, per 1 g/d | 1.06 (0.63, 1.78d) | ||
| Fatty acid 8:0 (caprylic acid) | |||
| Tertile 1 | 154 | 250,335 | 1.00 |
| Tertile 2 | 269 | 582,975 | 0.87 (0.70, 1.08) |
| Tertile 3 | 132 | 275,760 | 0.88 (0.64, 1.21) |
| Ptrend2 | 0.4 | ||
| Continuous, per 1 g/d | 0.98 (0.48, 1.98) | ||
| Fatty acid 10:0 (capric acid) | |||
| Tertile 1 | 218 | 392,511 | 1.00 |
| Tertile 2 | 142 | 296,423 | 0.94 (0.75, 1.17) |
| Tertile 3 | 195 | 419,296 | 0.90 (0.69, 1.17) |
| Ptrend2 | 0.5 | ||
| Continuous, per 1 g/d | 0.76 (0.48, 1.19) | ||
| Fatty acid 12:0 (lauric acid) | |||
| Tertile 1 | 199 | 358,279 | 1.00 |
| Tertile 2 | 180 | 357,789 | 1.01 (0.81, 1.26) |
| Tertile 3 | 173 | 393,005 | 0.87 (0.65, 1.17) |
| Ptrend2 | 0.2 | ||
| Continuous, per 1 g/d | 0.68 (0.44, 1.06) | ||
| Fatty acid 14:0 (myristic acid) | |||
| Tertile 1 | 183 | 331,578 | 1.00 |
| Tertile 2 | 195 | 394,287 | 1.04 (0.83, 1.31) |
| Tertile 3 | 177 | 384,455 | 0.99 (0.72, 1.35) |
| Ptrend2 | 0.7 | ||
| Continuous, per 1 g/d | 0.79 (0.47, 1.33) | ||
| Fatty acid 16:0 (palmitic acid) | |||
| Tertile 1 | 174 | 362,342 | 1.00 |
| Tertile 2 | 207 | 378,266 | 1.25 (0.98, 1.60) |
| Tertile 3 | 181 | 374,644 | 1.29 (0.86, 1.96) |
| Ptrend2 | 0.3 | ||
| Continuous, per 1 g/d | 0.84 (0.26, 2.72) | ||
| Fatty acid 18:0 (stearic acid) | |||
| Tertile 1 | 177 | 354,444 | 1.00 |
| Tertile 2 | 200 | 385,835 | 1.17 (0.92, 1.49) |
| Tertile 3 | 184 | 374,622 | 1.32 (0.88, 1.97) |
| Ptrend2 | 0.2 | ||
| Continuous, per 1 g/d | 0.68 (0.23, 1.96) | ||
1
Adjusted for age (continuous), total energy intake (kcal/d), fiber (g/d), BMI (<25, 25–29.9, ≥30), history of type 2 diabetes, alcohol intake (g/d), cigarette smoking (never, current, former; pack-y), aspirin use (nonregular or regular use, defined as ≥3 d/wk), vigorous physical activity (none, <5 h/wk, ≥5 h/wk), and years of education (≤12, 13–15, 16, ≥17 y).
2
Tests for linear trend were calculated by assigning the median of each category as scores.