TABLE 5.
Colorectal cancer risk across categories of total and individual MUFAs
| Total MUFAs, g/d | Cases, n | Person-y | HR (95% CI)1 |
|---|---|---|---|
| 0–<15.0 | 172 | 343,039 | 1.00 |
| 15.0–<21.5 | 159 | 306,157 | 1.05 (0.83, 1.35) |
| ≥21.5 | 233 | 466,980 | 1.00 (0.70, 1.43) |
| Ptrend2 | 0.9 | ||
| Continuous, per 10 g/d | 0.83 (0.30, 2.29) | ||
| Individual MUFAs | |||
| Fatty acid 16:1 (palmitoleic acid) | |||
| Tertile 1 | 176 | 362,159 | 1.00 |
| Tertile 2 | 199 | 374,057 | 1.19 (0.95, 1.50) |
| Tertile 3 | 188 | 377,579 | 1.26 (0.91, 1.75) |
| Ptrend2 | 0.2 | ||
| Continuous, per 1 g/d | 1.23 (0.62, 2.46) | ||
| Fatty Acid 18:1 (oleic acid) | |||
| Tertile 1 | 178 | 361,155 | 1.00 |
| Tertile 2 | 194 | 379,334 | 1.12 (0.87, 1.43) |
| Tertile 3 | 191 | 375,261 | 1.23 (0.82, 1.85) |
| Ptrend2 | 0.4 | ||
| Continuous, per 1 g/d | 1.04 (0.30, 3.57) | ||
| Fatty Acid 20:1 (gadoleic acid) | |||
| Tertile 1 | 159 | 334,821 | 1.00 |
| Tertile 2 | 195 | 396,244 | 1.01 (0.80, 1.26) |
| Tertile 3 | 210 | 383,173 | 1.01 (0.76, 1.33) |
| Ptrend2 | 0.9 | ||
| Continuous, per 1 g/d | 1.01 (0.61, 1.68) | ||
| Fatty acid 22:1 (erucic acid) | |||
| Tertile 1 | 200 | 412,020 | 1.00 |
| Tertile 2 | 152 | 320,232 | 0.86 (0.69, 1.07) |
| Tertile 3 | 206 | 374,347 | 0.89 (0.71, 1.11) |
| Ptrend2 | 0.4 | ||
| Continuous, per 1 g/d | 0.99 (0.26, 3.88) | ||
1
Adjusted for age (continuous), total energy intake (kcal/d), fiber (g/d), BMI (<25, 25–29.9, ≥30), history of type 2 diabetes, alcohol intake (g/d), cigarette smoking (never, current, former; pack-years), aspirin use (nonregular or regular use, defined as ≥3 d/wk), vigorous physical activity (none, <5 h/wk, ≥5 h/wk), and years of education (≤12, 13–15, 16, ≥17 y).
2
Tests for linear trend were calculated by assigning the median of each category as scores.