Figure 6. Associations Between eGFR Levels and Unfavorable Functional Outcomes in Ischemic Stroke Subtypes (Cardioembolic Stroke and Small Vessel Occlusion).

Odds ratios (ORs) for unfavorable functional outcomes after (A) cardioembolic stroke and (B) small vessel occlusion by estimated glomerular filtration rate (eGFR) (per mL/min/1.73 m²) using restricted cubic splines. Risk estimates were adjusted for age, sex, hypertension, diabetes, history of stroke, previous statin use, previous antiplatelet use, alteplase or endovascular treatment, premorbid modified Rankin Scale score, and initial National Institutes of Health Stroke Scale score. Solid lines represent the OR and dashed lines represent 95% CI. Knots were placed at 30, 45, and 60 mL/min/1.73 m² of eGFR. An eGFR of 60 mL/min/1.73 m² was used as a reference.