TABLE 3.

Sensitivity, specificity, positive and negative predictive values, and AUC for predicting neonatal and infant mortality using optimal cutoffs for anthropometric measures in singletons measured ≤72 h after birth (n = 21,174)¹

Characteristic		Cutoff	Total	No. died	Alive	Rate2	Sensitivity	Specificity	Youden Index	PPV3	NPV4
Neonatal mortality (≤8 d)
Length, cm	Optimal	(44.4)	20,773	287	20,486	20.1	60.0	85.9	45.9	8.0	99.1
	Harmonized	44.5	20,773	287	20,486	19.2	60.6	84.6	45.2	7.1	99.1
Weight, g	Optimal	(2220)	21,172	328	20,844	19.6	61.3	81.4	42.7	6.2	99.1
	Harmonized	2200	21,172	328	20,844	20.8	59.5	82.7	42.2	6.8	99.0
MUAC, cm	Optimal	(8.8)	21,127	309	20,818	20.3	58.3	80.6	38.9	5.9	98.9
	Harmonized	9.0	21,127	309	20,818	15.8	65.0	73.0	38.0	3.7	99.2
HC, cm	Optimal	(30.9)	21,007	307	20,700	24.5	53.4	88.7	42.1	10.6	98.7
	Harmonized	31.0	21,007	307	20,700	22.9	53.7	86.8	40.5	8.7	98.8
CC, cm	Optimal	(28.5)	21,042	305	20,737	25.6	55.7	88.5	44.2	11.3	98.7
	Harmonized	28.5	21,042	305	20,737	25.6	55.7	88.5	44.2	11.3	98.7
Infant mortality (≤365 d)
Length, cm	Optimal	(44.9)	20,773	530	20,243	32.6	54.0	81.3	35.3	8.9	98.1
	Harmonized	44.5	20,773	530	20,243	37.9	50.0	84.8	34.8	11.5	97.7
Weight, g	Optimal	(2220)	21,172	583	20,589	38.2	52.3	81.8	34.1	10.2	97.8
	Harmonized	2200	21,172	583	20,589	40.0	50.9	83.0	33.9	11.1	97.6
MUAC, cm	Optimal	(9.0)	21,127	563	20,564	31.8	56.0	73.2	29.2	6.4	98.1
	Harmonized	9.0	21,127	563	20,564	31.8	56.0	73.2	29.2	6.4	98.1
HC, cm	Optimal	(30.9)	21,007	556	20,451	44.9	42.4	88.9	31.3	15.3	97.0
	Harmonized	31.0	21,007	556	20,451	42.7	43.7	87.0	30.7	13.0	97.2
CC, cm	Optimal	(28.5)	21,042	554	20,488	47.8	43.9	88.7	32.6	16.3	96.9
	Harmonized	28.5	21,042	554	20,488	47.8	43.9	88.7	32.6	16.3	96.9

¹Optimal cutoff points based off Youden Index (35). CC, chest circumference; HC, head circumference; MUAC, midupper-arm circumference; NPV, negative predictive value; PPV, positive predictive value.

²Deaths per 1000 live births.

³

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