Table 1.
Immunophenotypic Characterization of T-Cell Subsets
| Cell Type | Markers Used in Hybrid Approach |
|---|---|
| T cells | CD3+ CD19− |
| CD8+ T cells | CD3+ CD19− CD8+ CD4− |
| CD8+ T cells: Effector | CD3+ CD19− CD8+ CD4− CD45RA+ CCR7− CD28− |
| CD8+ T cells: Effector memory (Tem) | CD3+ CD19− CD8+ CD4− CD45RA− CCR7− CD28− |
| CD8+ T cells: Central memory (Tcm) | CD3+ CD19− CD8+ CD4− CD45RA− CCR7+ CD28+ |
| CD8+ T cells: Naïve (Tn) | CD3+ CD19− CD8+ CD4− CD45RA+ CCR7+ CD28+ |
| CD4+ T cells | CD3+ CD19− CD8− |
| CD4+ T cells: Effector | CD3+ CD19– CD8– CD4+ CD45RA+ CCR7− CD28− |
| CD4+ T cells: Effector memory (Tem) | CD3+ CD19− CD8− CD4+ CD45RA− CCR7− CD28− |
| CD4+ T cells: Central memory (Tcm) | CD3+ CD19− CD8− CD4+ CD45RA− CCR7+ CD28+ |
| CD4+ T cells: Naïve (Tn) | CD3+ CD19− CD8+ CD4− CD45RA+ CCR7+ CD28+ |