Skip to main content
. 2022 Apr 12;50(8):4545–4556. doi: 10.1093/nar/gkac227

Figure 7.

Figure 7.

Islands and deserts affect the distribution of several chromosome modulators. Average ChIP-seq signal and 95% C.I. of (A) Top1-13myc and (B) Top2 at meiotic DSB hotspots in wild-type islands and deserts 3h after meiotic induction (15). (C) Average ChIP-seq signal and 95% C.I. of Smc4-Pk9 at axis attachment sites (20) in wild-type islands and deserts 3h after meiotic induction. Average ChIP-seq signal and 95% C.I. of (D) Top1-13myc and (E) Top2 at meiotic DSB hotspots in islands and deserts at the time of meiotic induction (0h) (15). (F) Average ChIP-seq signal and 95% C.I. of Smc4-Pk9 at axis attachment sites in islands and deserts in vegetatively cycling cells (27). (G) Table summarizing chromatin features associated with islands and deserts. Grey circles represent nucleosomes on purple DNA, indicating different occupancy and order. Purple boxes indicate ORFs of different sizes and spacing.