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. 2022 Jan 5;50(8):e43. doi: 10.1093/nar/gkab1275

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© The Author(s) 2022. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — The analysis for scMAGIC’s algorithm designs. Panel (A) shows the bar plot of the accuracy of scMAGIC and scMAGIC_single-round in four selected benchmark tests. Each benchmark test is represented by the first authors of the reference and the query dataset and the tissue of the query dataset, with the corresponding situation shown in parenthesis. In scMAGIC_single-round, only one round of RBC is performed. Panel (B) is similar to (A) except that scMAGIC is compared with scMAGIC_three-round in which three rounds of RBC are performed. Panel (C) is similar to (A) except that scMAGIC is compared with scMAGIC_no-Atlas in which no atlas expression matrix is included. Panel (D) shows the relationship between the accuracy of scMAGIC and the accuracy of the confidently validated query cells in the first-round of RBC. Panel (E) shows the relationship between the accuracy of the confidently validated query cells and the increase in CDI ranks. Panel (F) shows the relationship between the proportion of the confidently validated query cells and the increase of CDI ranks.