Table 2.

Proportional Hazards Models Predicting Risk in Dementia

	Model 1 (uncontrolled)	Model 2 (controlled)	Model 3 (mediated)
	HR [95% CI], p	HR [95% CI], p	HR [95% CI], p
cSES	0.689 [0.631–0.747], <.001	0.863 [0.762–0.965], .014	0.867 [0.867–0.959], .018
Age (years)	—	1.101 [1.088–1.113], <.001	1.099 [1.063–1.073], <.001
Gender	—	1.064 [0.855–1.273], .54	1.063 [0.763–0.896], .55
Race: African American/Black	—	2.708 [2.030–3.386], <.001	2.710 [1.951–2.484], <.001
Race: Otherwise identified	—	1.651 [0.785–2.516], .06	1.542 [1.192–1.822], <.001
Ethnicity	—	1.126 [0.726–1.810], .19	1.223 [0.921–1.312], .36
Education (years)	—	0.910 [0.876–0.944], <.001	0.910 [0.881–0.912], <.001
Year (baseline)	—	0.799 [0.634–0.964], .033	0.807 [0.887–1.043], .041
Conscientiousness	—	—	0.816 [0.895–0.975], <.001
Neuroticism	—	—	1.134 [1.052–1.144], .017
Openness	—	—	1.134 [0.946–1.048], .025
AIC	6,464.925	4,721.823	4,663.123
BIC	6,472.135	4,778.007	4,747.347

Note: cSES = childhood socioeconomic status; HR = hazard ratio; AIC = Akaike information criterion; BIC = Bayesian information criterion. Values were bolded to denote significance and make it easier for readers to identify this.