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. 2022 Apr 8;50(8):4450–4463. doi: 10.1093/nar/gkac246

Figure 2.

Figure 2.

Genome-wide localization of pMED1. (A) Threonine phosphorylation is specifically gained in mammals. Ortholog comparison of MED1 protein sequences surrounding human T1032 (green arrow) was performed in yeast, Caenorhabditis elegans, Drosophila, mouse and human. (B) A heatmap illustrates the distribution of pMED1 ChIP-seq signals on scaled RefSeq genes in human LNCaP-abl cells. (C) UCSC Genome Browser views of pMED1 occupancy on representative class II/III genes in human LNCaP-abl cells. (D) Comparison of expression levels among the three classes of genes.