Table 2.
Histopathological findings on biopsy
| Biopsy findings | Initial biopsy | Interval biopsy |
|---|---|---|
| (n = 59) | (n = 59) | |
| Total glomeruli (n) | 19 (13–27) | 19 (13–24) |
| Glomeruli (%) | ||
| Normal | 26 (17–48) | 39 (21–60)* |
| Necrotizing lesions | 25 (12–52) | 0 (0–0)* |
| Cellular crescents | 16 (0–33) | 0 (0–0)* |
| Fibrocellular crescents | 0 (0–14) | 0 (0–0)* |
| Globally sclerosed | 7 (0–18) | 22 (9–40)* |
| Interstitial inflammation | ||
| Nil | 0 (0%) | 11 (19%)* |
| Mild | 43 (73%) | 40 (68%) |
| Moderate | 8 (14%) | 7 (12%) |
| Severe | 8 (14%) | 1 (2%)* |
| IFTA | ||
| Mild | 32 (54%) | 21 (36%)* |
| Moderate | 17 (29%) | 19 (32%) |
| Severe | 10 (17%) | 19 (32%) |
Data are presented as median (interquartile range) or number of patients (%). Total glomeruli data are presented as number of glomeruli in sample. All other glomeruli data are presented as percentage of normal glomeruli. Analysis by Wilcoxon matched-pairs signed rank test or χ2 test as appropriate, *P <0.05. IFTA: interstitial fibrosis and tubular atrophy.