Table 3.
HR (95% CI) |
||||
---|---|---|---|---|
Univariable | Multivariable (model 1) | Multivariable (model 2) | Sensitivity analysis (followed yearly, n = 5975) | |
Age | 0.99 (0.98, 1.00) | 0.99 (0.97, 1.01) | 0.99 (0.98, 1.00) | 0.98 (0.97, 1) |
Sex | 0.80 (0.60, 1.06) | 0.75 (0.53, 1.07) | 0.72 (0.52, 1.00) | 0.63 (0.46, 0.87) |
BMI | 1.05 (1.02, 1.07) | |||
Obese | 1.76 (1.29, 2.40) | 1.49 (1.05, 2.13) | 1.64 (1.19, 2.26) | 1.49 (1.08, 2.06) |
Smoker | ||||
Never | Ref | |||
Current | 0.93 (0.65, 1.33) | |||
Past | 1.29 (0.92, 1.81) | |||
BSA | ||||
Continuous BSA (per 1% unit) | 1.02 (1.01, 1.03) | |||
Continuous BSA (per 5% unit) | 1.09 (1.04, 1.16) | 1.08 (1.01, 1.14) | ||
Mild (<3%) | Ref | Ref | ||
Moderate (3–10%) | 1.55 (1.12, 2.14) | 1.44 (1.02, 2.03) | 1.38 (0.98, 1.95) | |
Severe (>10%) | 2.41 (1.61, 3.6) | 2.01 (1.19, 3.13) | 1.82 (1.17, 2.84) | |
Anxiety | 1.00 (0.70, 1.42) | |||
Depression | 1.45 (1.08, 1.95) | 1.73 (1.21, 2.47) | 1.68 (1.21, 2.33) | 1.54 (1.12, 2.13) |
Diarrhoeal illness | 1.38 (1.00, 1.92) | |||
Duration 5+ years (vs <5) | 1.37 (1.01, 1.87) | |||
Hyperlipidaemia | 1.03 (0.65, 1.63) | |||
Hypertension | 1.14 (0.78, 1.65) | |||
Diabetes | 0.75 (0.41, 1.38) | |||
Liver disease | 0.92 (0.30, 2.89) | |||
COPD | 0.89 (0.28, 2.78) | |||
Fracture | 1.02 (0.74, 1.41) | |||
Anxiety | 1.00 (0.70, 1.42) | |||
Substance abuse | 0.85 (0.27, 2.65) | |||
Thyroid disease | 1.15 (0.63, 2.12) | |||
Pharyngitis | 1.19 (0.87, 1.63) | |||
Crohn’s disease | 1.05 (0.15, 7.52) |
Multivariable models include those covariates with a HR in the respective column. Model 1 includes BSA as a continuous variable (per increase of 5%), obesity (BMI ≥30 vs BMI <30), and depression (binary) and adjusts for age and sex. Model 2 includes BSA by category (mild, moderate and severe), obesity and depression and adjusts for age and sex. Psoriasis duration was not statistically significant in the multivariable model. BSA: body surface area; COPD: chronic obstructive pulmonary disease; HR: hazard ratio; Ref: reference group.