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. 2019 Sep 20;9(51):29873–29887. doi: 10.1039/c9ra06038c

Comparison of CoFe2O4/Cu(OH)2 catalytic activity with various catalysts reported for the one-pot synthesis of 2-phenyl-2-(4-phenyl-1H-1,2,3-triazol-1-yl)ethanol from styrene oxide, phenylacetylene and sodium azidea.

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Entry Catalyst system NaN3 (mmol) Conditions Time (h) Yield (%) Ref.
1 CoFe2O4/Cu(OH)2 (10 mol%) 1.2 H2O/60 °C 3.3 94 This work
2 Nano CuFe2O4 (10 mol%) 1.1 H2O/60 °C 6 87 29
3 Nano Fe2O3 (10 mol%) 1.2 H2O/100 °C 5 81 45
4 Cu nanoparticles/C (0.5 mol%) 1.1 H2O/70 °C 8 93 23
5 Cu(i)@phosphorated SiO2 (0.64 mol%) 1.1 H2O/60 °C 1 93 30
6 Copper(i)–zeolite (8 mol%) 1.2 H2O/r.t. 20 77 27
7 CuI (5 mol%) 1.1 PEG-400/r.t. 16 83 37
8 CuCl2 (10 mol%) 1 H2O/r.t. 5 35 31
9 Cu(NO3)2·3H2O (10 mol%) 1 H2O/r.t. 5 36.8 31
10 [Cu(bhppda)H2O]b (5 mol%) 1.2 Ascorbic acid/H2O/r.t. 2 90 28
11 CuSO4·5H2O (10 mol%) 1.2 Sodium ascorbate/H2O/r.t. 4 92 26
a

All reactions were carried out with styrene oxide (1 mmol) and phenylacetylene (1 mmol).

b

bhppda = N2,N6-bis(2-hydroxyphenyl)pyridine-2,6-dicarboxamidato dianion.