IC50 values for inhibition of the hQC enzyme by compounds 1_x and 3_x.
| Cpd | Structure | IC50 (μM) |
|---|---|---|
| 1_1 |
|
0.30 ± 0.09 |
| 1_2 |
|
0.11 ± 0.03 |
| 1_3 |
|
0.32 ± 0.10 |
| 1_4 |
|
0.42 ± 0.06 |
| 3_1 |
|
0.64 ± 0.09 |
| 3_3 |
|
0.45 ± 0.04 |
| 117 |
|
0.029 ± 0.004 |