Table 7.

Effect of different doses of administration of pendimethalin on morphological and nuclear changes in erythrocyte in Hypophthalmichthys nobilis (bighead carp).

Parameters (hours)	Groups
	T0 (0.0 mg/L)	T1 (0.25 mg/L)	T2 (0.50 mg/L)	T3 (0.75 mg/L)
Lobed nucleus (%)
72	0.19 ± 0.08	0.20 ± 0.04	0.21 ± 0.04	0.26 ± 0.07
96	0.19 ± 0.02	0.22 ± 0.04	0.24 ± 0.02	0.29 ± 0.03∗
120	0.21 ± 0.04	0.23 ± 0.02	0.25 ± 0.02	0.31 ± 0.05∗
Blabbed nucleus (%)
72	0.12 ± 0.04	0.14 ± 0.02	0.16 ± 0.04	0.21 ± 0.03
96	0.13 ± 0.02	0.16 ± 0.03	0.17 ± 0.03	0.33 ± 0.02∗
120	0.15 ± 0.04	0.17 ± 0.04	0.37 ± 0.07∗	0.76 ± 0.06∗
Vacuolated nucleus (%)
72	0.27 ± 0.06	0.28 ± 0.03	0.30 ± 0.01	0.30 ± 0.001
96	0.29 ± 0.06	0.30 ± 0.04	0.32 ± 0.02	0.41 ± 0.03∗
120	0.30 ± 0.06	0.31 ± 0.06	0.35 ± 0.07∗	0.47 ± 0.02∗
Notched nucleus (%)
72	0.18 ± 0.04	0.23 ± 0.03	0.29 ± 0.02∗	0.51 ± 0.01∗
96	0.17 ± 0.02	0.21 ± 0.01	0.34 ± 0.03∗	0.55 ± 0.06∗
120	0.17 ± 0.03	0.23 ± 0.01	0.43 ± 0.07∗	0.63 ± 0.07∗
Pear-shaped nucleus (%)
72	0.44 ± 0.01	0.46 ± 0.08	0.47 ± 0.01	0.48 ± 0.03
96	0.43 ± 0.02	0.47 ± 0.03	0.55 ± 0.02∗	0.69 ± 0.02∗
120	0.46 ± 0.06	0.48 ± 0.07	0.58 ± 0.02∗	0.72 ± 0.01∗
Micronucleus (%)
72	0.22 ± 0.07	0.23 ± 0.04	0.24 ± 0.03	0.67 ± 0.02
96	0.21 ± 0.04	0.23 ± 0.06	0.25 ± 0.02	2.72 ± 0.06∗
120	0.22 ± 0.05	0.25 ± 0.05	2.68 ± 0.06∗	3.75 ± 0.02∗

In each row, values (mean ± SE) bearing asterisks differ significantly (P < 0.05) from that of values in untreated (T0) fish.