Table 1.
Characterizations of blank and DOX-loaded PGEM and FA-GEM micelles.
| FA%a | Micelles | Size (d) (nm)b | Zeta potential (mV)b | DLE (%)c | DLC (%)d |
|---|---|---|---|---|---|
| 0% | PGEM | 11.24 ± 0.24 | ‒0.32 | 86.31 | 7.84 |
| PGEM/DOX | 8.8 ± 0.96 | ‒1.14 | |||
| 1% | FA-PGEM | 11 ± 0.33 | ‒3 | 80.13 | 7.28 |
| FA-PGEM/DOX | 10.28 ± 0.98 | ‒1.36 | |||
| 5% | FA-PGEM | 11.08 ± 0.13 | ‒3.96 | 82.43 | 7.49 |
| FA-PGEM/DOX | 9.17 ± 1.04 | ‒2.29 | |||
| 10% | FA-PGEM | 12.07 ± 1.01 | ‒0.85 | 95.6 | 8.69 |
| FA-PGEM/DOX | 10.17 ± 0.86 | ‒1.45 | |||
| 20% | FA-PGEM | 9.96 ± 1.7 | ‒1.54 | 96 | 8.72 |
| FA-PGEM/DOX | 11.17 ± 0.53 | ‒1.91 |
Percentage of FA-PGEM mixed with PGEM.
Measured by dynamic light scattering particle sizer.
DLE = Drug loading efficiency as measured by UV spectrophotometer.
DLE = Drug loading capacity of micelle calculated using DLC.