Table 7. Cutaneous malignancies and cannabinoids.

CBD, cannabidiol.

Skin cancer	Comment	Ref
Kaposi sarcoma	Synthetic cannabinoid WIN-55,212-2 can induce apoptosis of Kaposi sarcoma-derived cell lines. CBD inhibits tumor cell growth and angiogenesis among Kaposi sarcoma-affected endothelial cells	[2]
Melanoma	Endocannabinoids, phytocannabinoids, and synthetic cannabinoids decrease non-melanoma skin cancer and melanoma growth in vitro and in vivo through cannabinoid receptor-dependent and independent pathways	[9]
Non-melanoma skin cancer	Mice deficient in cannabinoid receptors 1 and 2 had significantly lower rates of ultraviolet B-induced inflammation and skin carcinogenesis than wild-type mice	[9]