Table 3.
Association risk of comorbidities and lifestyle factors with risk of IRF development.
| HR | 95% CI | |
|---|---|---|
| Age | ||
| 30–49 years | 1.00 | |
| 50–64 years | 5.12 | (1.85–14.15) |
| 65–74 years | 16.43 | (6.04–44.73) |
| Sex (male) | 1.09 | (0.79–1.50) |
| Smoking status | ||
| Active smoker | 1.00 | |
| Ex-smoker | 0.93 | (0.57–1.53) |
| Never smoker | 0.78 | (0.47–1.28) |
| Regular physical activity (no) | 0.97 | (0.70–1.35) |
| High-risk alcohol consumption (no) | 1.28 | (0.74–2.20) |
| Adherence Mediterranean diet score (no) | 0.75 | (0.54–1.04) |
| Daily consumption of fruit or vegetables (no) | 1.18 | (0.66–2.10) |
| Metabolic syndrome (no) | 1.14 | (0.82–1.59) |
| Waist circumference (cm) | 1.39 | (0.98–1.98)- |
| BMI ≥ 30 (kg/m2) | 1.21 | (0.87–1.68) |
| Hypertension, (no) | 2.08 | (1.38–3.12) |
| Total cholesterol ≥ 250 mg/dL* | 1.15 | (0.74–1.81) |
| Low HDL-cholesterol mg/dL* | 1.28 | (0.86–1.91) |
| Triglycerides ≥ 200 mg/dL | 1.00 | (0.68–1.45) |
| Use of ACEIs or ARBs (no) | 1.82 | (1.31–2.52) |
Model 1 (sex- and age-adjusted).
*HDL-C of < 40 mg/dL in men or < 50 mg/dL in women.