Substrate scope with respect to the o-phenylenediaminea.
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Reaction conditions: 1 (0.2 mmol), 2a (0.5 mmol), 4-ADPA (0.2 mmol), paraformaldehyde (0.8 mmol), TCE (0.7 mL), H2O (0.2 mL), 130 °C, 3 h, air. Isolated yield.
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Reaction conditions: 1 (0.2 mmol), 2a (0.5 mmol), 4-ADPA (0.2 mmol), paraformaldehyde (0.8 mmol), TCE (0.7 mL), H2O (0.2 mL), 130 °C, 3 h, air. Isolated yield.