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. 2022 May 5;12:7366. doi: 10.1038/s41598-022-11335-0

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The mean latency, in seconds, to the platform on the four training days of MWM task between the control and disrupted mice (A). The latency in seconds to the target quadrant between the control and the disrupted animals on the testing day (day 5) (B). The mean number of passing through the target area by the control and disrupted animals on the testing day (day 5) (C). The time spent in the target quadrant (quadrant 1) by control and disrupted animals on testing day (day 5) (D). The platform was located in quadrant 1 of the apparatus during training. Error bars represent the standard error of the mean. * = p < 0.05. N = 12/group.