Table 4.

Change in c-statistic for predicting 2- and 5-year risk of kidney failure needing replacement therapy when adding kidney injury marker 1 (KIM-1 ), tumor necrosis factor receptor 1 (TNFR-1 ), individually and together, to a model including the kidney failure risk equation score.

	2-year risk of KFRT (N Events = 22)		5-year risk of KFRT (N Events = 69)
	c-statistic	P	c-statistic	P
KFRE (4 variable)	0.832	base model	0.859	base model
KFRE + KIM-1	0.852	0.48	0.853	0.76
KFRE + TNFR-1	0.844	0.46	0.836	0.22
KFRE + KIM1 + TNFR-1	0.861	0.28	0.868	0.61

Abbreviations: KFRE, kidney failure risk equation; KFRT, kidney failure needing replacement therapy

P-value compares c-statistics to base model