TABLE 7.

Genetic linkage of grlA and grlB mutations and resistance by transformation: outcross of mutations^a

Donor strainb	Genotype	MIC (μg/ml) for resistant transformants		% Resistant transformants (no. of resistant transformants/no. of total transformants)
		GAT	CIP
G1332	grlA (Lys23Asn) Ω(chr::Tn917lac)2	0.25	0.5	22 (23/105)
GB331	grlB (Pro25His) Ω(chr::Tn917lac)2	0.5	1.0	37 (22/60)

^aAbbreviations: GAT, gatifloxacin; CIP, ciprofloxacin. 

^bRecipient ISP794 grlA⁺ grlB⁺ (MIC of GAT, 0.064 μg/ml; MIC of CIP, 0.125 μg/ml).