Surface element compositions of the materials studied in this worka.
| Material | Element weight (%) | Element atom (%) | ||||
|---|---|---|---|---|---|---|
| Carbon | Nitrogen | Oxygen | Carbon | Nitrogen | Oxygen | |
| WCG | 26.10 ± 2.85 | 38.03 ± 0.57 | 35.88 ± 2.27 | 30.45 ± 3.09 | 38.09 ± 0.87 | 31.47 ± 2.23 |
| FC WCG-3%b K30 | 33.70 ± 1.62 | 26.65 ± 1.28 | 39.66 ± 0.34 | 39.04 ± 1.75 | 26.45 ± 1.35 | 34.50 ± 0.39 |
| FC WCG-6%b K30 | 45.27 ± 1.29 | 23.91 ± 1.66 | 30.83 ± 2.95 | 50.91 ± 1.17 | 23.05 ± 1.47 | 26.05 ± 2.65 |
| FC WCG-9%b K30 | 52.21 ± 2.22 | 21.13 ± 1.45 | 26.66 ± 0.77 | 57.78 ± 2.20 | 20.07 ± 1.47 | 22.16 ± 0.73 |
WCG, wet-granulation citric acid granules; FC, fluid-bed coating; K30, PVP-K30.
% was the PVP content (w/w) and the PVP spray solution concentration (w/v) was 13%.