Fig. 7. Effect of tannic acid (TA) on Nrf2-keap1 pathway in diquat-induced mice. CON, control mice; DIQ, diquat-treated mice; LTA, mice pretreated with 2.5 mg kg⁻¹ TA and treated with diquat; MTA, mice pretreated with 5 mg kg⁻¹ TA and treated with diquat; HTA, mice pretreated with 10 mg kg⁻¹ TA and treated with diquat; (A)–(D) the gene expression of nuclear factor erythroid 2-related factor 2 (NRF2), Kelch like-ECH-associated protein 1 (KEAP1), NADPH dehydrogenase (NQO-1), heme oxygenase (HO-1) in jejunum. (E) The protein expression of NRF2, KEAP-1 and β-actin. (F) and (G) The protein expression of KEAP1, NRF2 in jejunum. Values are expressed as mean ± SEM, n = 10. ^a,bMeans of the bars with different letters were significantly different among groups (P < 0.05).