Table 1.
Characteristics of 26 included studies.
| Author, year | Country | Study design | No. of subjects | Range of/average age | Gender (female %) | BMI as confounder | OA definition | HTN definition |
|---|---|---|---|---|---|---|---|---|
| Knee OA | ||||||||
| Konstari, 2019 | Finland | Cohort | 6274 | ≥30 | 50.1% | Yes | Symptomatic | SBP ≥130 mmHg or DBP ≥85 mmHg or antihypertensive medication |
| Venkatachalam, 2018 | India | CS | 1986 | ≥18 | 63.5% | No | Symptomatic | SBP >140 mmHg and/or DBP >90 mmHg |
| Niu, 2017 | USA | Cohort | 991 | 54.2 | 55.1% | Yes | Radiographic/symptomatic | ≥130/85 mmHg or use of antihypertensive medications |
| Kim, 2016 | Korea | CS | 9514 | ≥50 | 57.3% | Yes | Radiographic | Prehypertension: 120–139/80-89 mmHg Hypertension: ≥140/90 mmHg or use of antihypertensive medications |
| Li, 2016 | China | CC | 151 | 50–80 | 81.5% | No | Radiographic | Prehypertension: SBP 120–139 or DBP 80-89 Stage 1 hypertension: SBP 140–159 or DBP 90-99 Stage 2 hypertension: SBP ≥160 or DBP ≥100 |
| Liu, 2016 | China | CS | 3428 | ≥40 | 51.5% | Yes | Symptomatic | ≥140/90 mmHg or use of antihypertensive medications |
| Maddah, 2015 | Iran | CS | 625 | 54.64 | 80.0% | No | Radiographic | ≥130/85 mmHg or use of antihypertensive medications |
| Shin, 2014 | Korea | CS | 2363 | ≥50 | 57.4% | Yes | Radiographic | ≥130/85 mmHg or use of antihypertensive medications |
| Han, 2013 | Korea | CC | 2234 | 40–91 | 54.3% | No | Symptomatic | ≥130/85 mmHg or use of antihypertensive medications |
| Yoshimura, 2012 | Japan | Cohort | 1384 | 63.9 | 66.3% | Yes | Radiographic | ≥130/85 mmHg |
| Inoue, 2011 | Japan | CS | 795 | 30–86 | 62.9% | No | Radiographic | ≥130/85 mmHg |
| Kim, 2010 | Korea | CS | 504 | ≥50 | 54.4% | Yes | Radiographic/symptomatic | ≥140/90 mmHg |
| Hart, 1995 | UK | CS | 979 | 45–64 | 100% | Yes | Radiographic/symptomatic | use of antihypertensive medications |
| Bagge, 1991 | Sweden | CS | 340 | ≥79 | 60.3% | Yes | Radiographic | DBP ≥110 mmHg or use of antihypertensive medications |
| Hand OA | ||||||||
| Strand, 2017 | USA | Cohort | 1089 | 59.2 | 51.8% | Yes | Radiographic | ≥130/85 mmHg or on medication |
| Frey, 2016 | USA | CC | 27000 | 30–90 | 74.2% | No | Medical record | Medical record |
| Wang, 2016 | China | CS | 6218 | ≥40 | 53.1% | No | Radiographic/symptomatic | Clinical diagnosis or use of antihypertensive medications |
| Tomi, 2016 | France | CS | 301 | 53.4 | 12.0% | No | Radiographic | ≥140/90 mmHg |
| Dahaghin, 2007 | Netherland | CS | 3585 | ≥55 | 58.2% | Yes | Radiographic | ≥160/100 mmHg or use of antihypertensive medications |
| Generalized OA | ||||||||
| Alenazi, 2019 (unspecified) | Unspecified | CS | 3855 | 66.43 | 60.9 | Yes | Symptomatic | Medical record |
| Kovari, 2019 (hand and knee) | Hungarian | CC | 400 | 65.47 | 100% | No | Symptomatic | Medical record |
| Askari, 2017 (knee and/or hip) | Iran | CC | 393 | 54.6 | 81.9% | Yes | Radiographic | ≥130/85 mmHg |
| Oh, 2011 (shoulder OA) | Korea | Cohort | 679 | 71.8 | 58.3% | No | Radiographic | Medical record |
| Engstrom, 2009 (knee and/or hip) | Sweden | Cohort | 5171 | 57.5 | 58.5% | Yes | Radiographic | ≥130/85 mmHg or use of antihypertensive medications |
| Sowers, 1996 (knee and/or hand) | USA | CS | 573 | 24–45 | 100% | Yes | Radiographic | SBP ≥ 124 mmHg or self-reported |
| Bae, 2015 (unspecified) | Korea | CS | 17128 | ≥20 | 57.6% | Yes | Symptomatic | Prehypertension: 120–139/80-89 mmHg Hypertension: ≥140/90 mmHg or use of antihypertensive medications |
Abbreviations: HTN: hypertension; OA: osteoarthritis; BMI: body mass index; CS: cross-sectional study; CC: case–control study; DBP: diastolic blood pressure; SBP: systolic blood pressure.