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Naringin promote the quality repair of cartilage defects, and acellular dermal matrix promote the structure repair of cartilage defects, and satisfactory repair effect can be obtained by combined application, This repair effect may be associated with naringin activating TGF-β/ALK5/Smad signaling pathways, resulting in increased expression of TGF-β2, TGF-β3 and SOX9 in cartilage defects.
