Table 4.

Intra-group (paired t-test) and inter-group (independent t-test) analyses on the basis of estimated histopathology (HP) and scanning electron microscopy (SEM) scores of cellular events for the animal groups over time (mean ± SD).

Study interval	HP		IS t-test	SEM		IS t-test
	Group I	Group II		Group I	Group II
14 days	11.67 ± 1.0†	10.1 ± 0.78	t=3.677∗	12.2 ± 1.09†,¶	9.44 ± 0.73	t=6.35∗
28 days	11.1 ± 0.78†,¶	6.67 ± 1.2	t=9.067∗	11.2 ± 0.67†,#	6.89 ± 0.93	t=11.377∗
42 days	10.2 ± 0.83¶	2.1 ± 0.93†	t=19.51∗	10.67 ± 0.7#	3.33 ± 0.5	t=25.403∗
90 days	12.89 ± 0.78	1.3 ± 0.71†	t=32.888∗	13.2 ± 0.67¶	1.89 ± 0.6	t=37.882∗
Gross score	45.89 ± 1.36	20.33 ± 1.32	t=40.345∗	47.33 ± 1.22	21.56 ± 1.51	t=39.788∗

Same superscripts (^†, ^¶, and ^#) indicate statistically insignificant difference (P>0.05) in a group with time. ^∗Significant inter-group relation at specific time interval (P<0.05); SD: standard deviation; IS: independent sample.