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Best ORR and CBR (patients with measurable disease at baseline). ORR was calculated by CR + PR; CBR was calculated by CR + PR + (SD ≥ 24 weeks). CBR, clinical benefit rate; CNS, central nervous system; CR, complete response; ECOG PS, Eastern Cooperative Oncology Group performance status; ORR, overall response rate; PC, prior chemotherapy; PD, progressive disease; PR, partial response; SD, stable disease; VM, visceral metastases.
