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. 2022 Apr 25;2022:9865606. doi: 10.1155/2022/9865606

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Copyright © 2022 Yuyan Xu et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Inhibiting the Nrf2 can reduce the oxidative stress and alleviates arsenic-induced liver damage in MIHA cells. The in vitro results were based on 6 independent experiments. All data are presented as mean ± standard deviation. ^∗, P < 0.05. (a) The relative mRNA expression of Nrf2 and GPX4. (b) The western blot for Nrf2, p-Nrf2, and GPX4. (c) The relative mRNA expression of Nrf2, p-Nrf2, and GPX4. (d) The concentration of oxidative stress-related indicators. (e) The content of liver damage-related indicators.