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Frequently used immune checkpoint inhibitors and their molecular targets.
| Molecular target | Generic drug name | Brand name |
|---|---|---|
| PD-1 | Pembrolizumab | Keytruda |
| Nivolumab | Opdivo | |
| PD-L1 | Atezolizumab | Tecentriq |
| Durvalumab | Imfinzi | |
| Avelumab | Bavencio | |
| CTLA-4 | Ipilimumab | Yervoy |
PD-1, programmed cell death-1; PD-L1, programmed cell death-ligand 1; CTLA-4, cytotoxic T-lymphocyte-associated protein-4.
