. 2019 Oct 21;9(58):33761–33774. doi: 10.1039/c9ra05661k

Observed and estimated anti-proliferative activity values for the tested piperidinecarboxamides 24–47 according to the BMLR-QSAR models.

Entry	Compd	HCT116			MCF7			A431
Entry	Compd	Observed IC₅₀, μM	Estimated IC₅₀, μM	Error^a	Observed IC₅₀, μM	Estimated IC₅₀, μM	Error^a	Observed IC₅₀, μM	Estimated IC₅₀, μM	Error^a
1	24	1.08	1.17	−0.09	1.83	1.39	0.44	2.49	1.94	0.55
2	25	1.03	0.95	0.08	2.09	2.50	−0.41	2.51	2.21	0.30
3	26	1.43	1.39	0.04	2.48	2.50	−0.02	2.83	2.80	0.03
4	27	1.61	1.29	0.32	2.95	2.62	0.33	2.56	4.25	−1.69
5	28	1.31	1.60	−0.29	2.58	2.51	0.07	2.58	2.65	−0.07
6	29	0.70	0.72	−0.02	1.33	1.58	−0.25	1.29	1.08	0.21
7	30	0.58	0.60	−0.02	1.13	0.89	0.24	0.64	0.92	−0.28
8	31	1.03	0.88	0.15	1.44	1.54	−0.10	1.24	1.81	−0.57
9	32	1.04	0.91	0.13	2.35	2.12	0.23	1.31	1.39	−0.08
10	33	1.13	0.93	0.20	2.14	2.00	0.14	1.45	1.76	−0.31
11	34	0.56	0.59	−0.03	2.34	2.07	0.27	1.27	1.00	0.27
12	35	0.56	0.53	0.03	1.36	1.46	−0.10	1.20	1.07	0.13
13	36	0.62	0.69	−0.07	1.71	2.18	−0.47	1.31	0.98	0.33
14	37	0.57	0.63	−0.06	2.32	2.51	−0.19	1.18	1.03	0.15
15	38	0.56	0.56	0.00	2.16	2.53	−0.37	1.33	1.38	−0.05
16	39	1.44	1.36	0.08	3.96	4.46	−0.50	2.57	2.79	−0.22
17	40	2.73	2.87	−0.14	5.10	4.52	0.58	4.90	6.04	−1.14
18	41	2.26	3.71	−1.45	4.58	4.87	−0.29	2.64	3.32	−0.68
19	42	22.98	3.43	19.55	4.90	5.10	−0.20	8.75	6.78	1.97
20	43	1.23	1.29	−0.06	3.96	4.38	−0.42	2.72	3.09	−0.37
21	44	1.11	0.94	0.17	4.17	3.94	0.23	2.85	3.18	−0.33
22	45	1.38	1.55	−0.17	5.85	5.82	0.03	11.35	10.62	0.73
23	46	1.50	1.71	−0.21	5.73	5.13	0.60	8.83	5.63	3.20
24	47	1.29	1.72	−0.43	4.89	4.74	0.15	7.98	6.53	1.45

Error is the difference between the observed and estimated bio-activity values.