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. 2022 Apr 21;10(4):e32557. doi: 10.2196/32557

Table 2.

Research app characteristics.

Author App name Sample size (age) Experiment (participant sample size) Platforma (private or public) App purpose (direct or indirect) Intervention period Major outcome indices
Daly et al [38] PhysiApp-patient portal 20 (>65 years) App (20) Android (public) Remotely delivers and monitors an individually tailored, home-based multicomponent exercise program (indirectb) 8 weeks Feasibility, usability, physical activity enjoyment, changes in lower extremity function, and level of physical activity
Bhatia et al [44] Manage My Pain 246 (mean age 57, SD 15 years) App (111); no app (135) Android and iOS (public) Measures and monitors pain, function, and medication use (indirect) 92-183 days Anxiety, depression, pain catastrophizing, satisfaction, daily opioid consumption, engagement
Cairo et al [59] Vida app 127 (>18 years) App (66); no app (61) Android and iOS (public) Improves wellness outcomes for survivors of breast cancer (indirect) 6 months Physical activity, diary patterns, fatigue, and depression improvement
Hauser-Ulrich et al [53] SELMA-Chatbot 102 (mean age 43.7 years) App (59); no app (43) Android and iOS Promotes self-management of chronic pain (indirect) 12 weeks Pain-related impairment, intention to change behavior, and pain intensity
Suso-Ribera et al [51] Pain Monitor 87 App (43); no app (44) N/Ac (private) Improves existent medical treatments for patients with chronic musculoskeletal pain (indirect) 4 weeks Pain severity and interference, fatigue, depressed mood, anxiety, and anger
Licciardone et al [36] N/A 102 (mean age 51 years) App (52); no app (50) N/A Self-management of health‐related quality of life (indirect) 3 months Change in the SPADEd cluster score, changes in low back pain intensity, and back‐related disability
Geerds et al [35] N/A 24 (older adults >60 years) App (24); no app (24) N/A (private) Monitors postoperative functional outcome after hip fracture (indirect) 12 and 18 weeks after surgery Usability
Bailey et al [47] Hinge Health app 10,264 (mean age 43.6 years) App (10,264) N/A (private) Provides education, sensor-guided exercise therapy, and behavioral health support with one-on-one remote health coaching (indirect) 12 weeks Pain measured by the Visual Analog Scale, engagement levels, program completion, program satisfaction, condition-specific pain measures, depression, anxiety, and work productivity
Ryan et al [48] Striving app, Boning up 290 (40-60 years) App (84); e-book (84); no app (84) Android and iOS (private) Provides information and feedback and monitors behavior change (directe) 12 months Bone mineral density and trabecular bone scores
Papi et al [32] Nymbl 35 (≥55 years) App (35) N/A (private) Trains balance in the older population (indirect) 3 weeks for all, with optional follow-up for 3 weeks Physical activity level and adherence and IPAQf questionnaire
Sandal et al [45] selfBack 51 (mean age 45.5, SD 15.0 years) App (51) N/A (private) Improves self-management of low back pain (indirect) 6 weeks Pain-related disability (RMDQg) and multiple self-reported outcomes
Urena et al [33] m-SFT 7 (53-61 years); the system usability was evaluated by 34 health experts (mean age 36.64 years) App (7) Android (private) Easy-to-use tool for a health practitioner to record and assess the physical condition of older adults (indirect) N/A Usability questionnaire
Li et al [49] Caspar Health App or Website 31 (≥60 years) App (15); no app (16) Android and iOS (public) Postfracture telerehabilitation (direct) 3 weeks Motor performance, functional performance, and fall efficacy; degree of independence in ADLh performance
Kim et al [40] Fracture Liaison Service 60 (>60 years) App (60) Android and iOS (public) Fall prediction and monitoring (direct) N/A Usability
Amorim et al [37] Fitbit (activity tracker) and IMPACT app 68 (mean age 58.4, SD 13.4 years) App (34); no app (34) Android and iOS (public) Reduces care seeking, pain, and disability in patients with chronic low back pain after treatment discharge (indirect) 15 months Care seeking, pain levels, and activity limitation
Subasinghe et al [57] Tap4Bone: MyFitnessPal, Nike Training Club, and QuitBuddy 35 (mean age 23.1 years) App (18); no app (17) Android and iOS (public) MyFitnessPal is a free calorie counter app that helps people track their diet and exercise; Nike Training Club is a free app comprising >100 full-body workouts; QuitBuddy is a smoking cessation internet-based app (indirect) 9 weeks Feasibility and compliance
Arkkukangas et al [34] OEP app 12 (70-83 years) App (12) N/A (private) Fall prevention (indirect) 6 weeks Questionnaire and behavior change
Shebib et al [50] DCP with sensors 177 (mean age 43, SD 11 years) App (113); no app (64) N/A (private) Aids self-management by engaging patients, and scales personalized therapy for patient-specific needs (indirect) 12 weeks ODIi, Korff Pain, and Korff disability
Bedson et al [39] Keele pain recorder 21 (>18 years) App (21) Android (public) Records pain levels, interference, sleep disturbance, analgesic use, mood, and side effects (indirect) 28 days Usability and acceptability
Hou et al [55] eHealth 168 (18-64 years) app (84); no app (84) N/A (private) Telerehabilitation and self-management interventions (indirect) 3, 6, and 12 months Disease-specific questionnaire (ODI), Visual Analog Scale to record back pain, measures of mental health and life status, which included the EuroQol 5-Dimension health questionnaire
Saran et al [46] N/A 927 (20-80 years) App (927) N/A (private) Monitors physical activity (indirect) 1 week Home physical activity
Chhabra et al [54] Snapcare 93 mean) age 41.4, SD 14.2 years) App (45); no app (48) Android (private) Monitors patient’s daily activity levels and symptomatic profile (indirect) 12 weeks Pain and disability
Jakobsen et al [31] My Osteoporosis Journey 18 (50-65 years) App (18) Android and iOS (private) Provides information and usability questionnaires (direct) 12 weeks Satisfaction with the app and risk calculation
Lambert et al [56] PhysiotherapyExercises 80 (34-59 years) App (40); no app (40) N/A (private) Home exercise programs (indirect) 4 weeks Self-reported exercise adherence, The Patient-Specific Functional Scale, degree of disability, and patient satisfaction with health care service
Rasche et al [43] Aachen fall prevention app 79 (>50 years) App (79) Android and iOS (private) Self-assessment of older patients at risk for ground-level falls (indirect) 1 year Objective fall risk and the self-assessed subjective fall risk
Park et al [52] Strong bone, Fit body 82 (<25 years; women) App (36); no app (38) Android (private) Provides feedback and records activity and nutrition (direct) 20 weeks Bone mineral density, minerals, biochemical markers, food intake diary, knowledge, health belief, and self-efficacy
Tay et al [41] Calci-app 40 (18-25 years) App (40) Android and iOS (private) Usability questionnaires (direct) 5 days Dietary calcium intake
Goodman et al [58] VDC-app 109 (18-25 years) App (59) iOS (private) Provides information and feedback and monitors behavior change (direct) 12 weeks Vitamin D intake, knowledge, perceptions of vitamin D, blood concentrations of 25(OH)D3
Singler et al [42] AOTrauma’s orthogeriatrics 920 (health professionals) App (920) Android and iOS (public) Delivers the app to surgeons, trainees, and other health care professionals to measure use and evaluate the impact on patient care (direct) Web-based one-time evaluation Rating of app and usability

aApp is available to the public in app stores, or app is not available to the public in app stores.

bThe study has an indirect relation to osteoporosis.

cN/A: not applicable.

dSPADE: sleep disturbance, pain, anxiety, depression, and low energy or fatigue.

eThe study or app has a direct relation to osteoporosis.

fIPAQ: International Physical Activity Questionnaire.

gRMDQ: Roland-Morris Disability Questionnaire.

hADL: activities of daily living.

iODI: Oswestry Disability Index.