Table 2.

Associations of Raincoat mobile phone app use and HIV PrEP^a adherence (tenofovir diphosphate level ≥700 fmol/punch) at months 3 and 6.

App users			PrEP adherent, n (%; 95% CI)		Unadjusted				Adjustedb
					Odds ratio (95% CI)		P value		Odds ratioc (95% CI)		P value
At 3 months
	YFSd only (n=79)	40 (50; 39.6-61.6)		1.0		N/Ae		N/A		N/A
	YFS and infrequent app use (n=53)	29 (55; 41.3-68.1)		1.8 (0.6-2.4)		.64		1.1 (0.5-2.4)		.84
	YFS and frequent app use (n=21)	14 (67; 46.5-86.8)		2.0 (0.7-5.4)		.19		1.8 (0.6-5.4)		.59
At 6 months
	YFS only (n=68)	30 (44; 32.3-55.9)		1.0		N/A		N/A		N/A
	YFS and infrequent app use (n=47)	21 (45; 30.5-58.9)		1.0 (0.5-2.2)		.95		0.8 (0.4-1.9)		.64
	YFS and frequent app use (n=22)	13 (59; 38.5-79.6)		1.8 (0.7-4.8)		.22		1.8 (0.6-5.3)		.27

^aPrEP: pre-exposure prophylaxis.

^bAdjusted by gender identity (men who have sex with men vs transgender women), age at enrollment (15-17 vs 18-19) (years), number of sex in the past month at enrollment interviewed (0 vs 1 and ≥2), and self-perceived HIV acquisition risk at enrollment.

^cUnadjusted odds ratio (95% CI) of adjusted variables in footnote^a, as previously published [34].

^dYFS: youth-friendly services.

^eN/A: not applicable (reference).